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KMID : 0374019880110010049
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Ewha Medical Journal
1988 Volume.11 No. 1 p.49 ~ p.57
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Experimental Study on Microvascular Anastomosis without Sutures Using Fibrin Glue
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Abstract
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Since the anastomosis by suture most widely used in microvascular. surgery has two major disadvantage in that it may inflict considerable damage on the vessel ends and that the suture material may function as a thrombogenic agent, much effort has been spent in developing methods of anastomosis in which the number of sutures is reduced to minimum. As one of such efforts, we performed the following experiment using only fibrin glue without leaving out any suture material. First, we divided the femoral artery of the rats and telescoped the proximal end into the distal end by traction of two U-shaped guide sutures. Next, we removed the guide sutures and dropped the fibrinogen and the thrombin solution dissolved in the distilled water and calcium chloride respectively on the telescoped area. After waiting for 5 minutes, vascular clamps were released.
The results we got from the gross and histological examination showed that this method has advantage as follows
1) This method is easier and speedier than suture technique.
2) Suture material was not exposed into the lumen.
3) There was less vessel trauma owing to fewer sutures and less manipulation of the vessel end.
4) Blood leakage from the anastomosal si*Q was prevented.
5) There was no aneurysm.
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